Structural Biology · AI Research Platform

Predict. Compare.
Understand.

Surface 2 brings AlphaFold-class protein structure prediction, multi-model ensemble comparison, and disease-variant interpretation to every researcher — no GPU required.

Used by researchers at 12+ institutions · No GPU required · Results in minutes
AlphaBetaGammaDelta
pLDDT
Sequence
MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFE...
Length
147 residues
Alpha completed — pLDDT 91.2
3 models running
200M+
Proteins in AlphaFold database
4
Model ensemble (Alpha, Beta, Gamma, Delta)
<2min
Average structure prediction time
7
Therapeutic areas covered
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8 steps · No sign-up required · Interactive

Everything you need for structural biology research

Multi-Model Ensemble

Run Alpha, Beta, Gamma, and Delta simultaneously and compare predictions side-by-side in the built-in structure viewer.

Variant Impact Scoring

Visualise wild-type vs mutant structures with pLDDT confidence overlays and AlphaMissense pathogenicity scores.

Drug Candidate Ranking

Surface AI-predicted drug-disease associations with confidence scores and DrugBank cross-references.

Report Builder

Assemble publication-ready reports from structure predictions, evidence snippets, and model comparison outputs.

Disease Profile Engine

Explore gene-disease associations, mechanism hypotheses, and evidence snippets linked to live PubMed citations.

No GPU Required

All inference runs on Surface 2's managed compute layer. Researchers access results through the browser.

Built for every stage of research

USMLE · FMGE · PLAB

Understand pathophysiology at molecular level

From sickle cell polymerisation to antibiotic resistance — visualise the exact structural changes behind the mechanisms you're studying.

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Publication-grade

Build a structural biology portfolio

Run mini research projects with reproducible outputs, EvidenceLog tracking, and structured 1,500-word reports suitable for residency applications.

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Enterprise · RaaS

Full-scale pipeline automation

7 therapeutic area pipelines — oncology, rare disease, AMR, vaccine design, neurodegeneration, cardiology, pediatrics. Structured output in PDF, JSON, and DOCX.

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From sequence to insight in minutes

1
Input your target

Enter a gene name, paste a FASTA sequence, or select from 7 therapeutic area templates.

2
Select models

Choose from Alpha, Beta, Gamma, or Delta — or run all four as an ensemble.

3
Run analysis

Surface 2's compute layer runs prediction and co-folding. Live progress in the Run Monitor.

4
Explore results

Interactive 3D structure, confidence overlays, drug candidates, evidence snippets, and exportable reports.

Simple, transparent pricing

Researcher
Free
  • Alpha model only
  • 5 runs/month
  • PDF export
  • Community support
Get started free
Most Popular
ResearcherPlus
$29/mo
  • All 4 models
  • 50 runs/month
  • All export formats
  • Priority compute
  • Report Builder
  • Evidence log
Start ResearcherPlus
Enterprise / RaaS
Custom
  • Unlimited runs
  • All 7 therapeutic pipelines
  • Dedicated compute
  • API access
  • SLA
  • White-label option
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