Structural Biology · AI Research Platform

Predict. Compare.
Understand.

Surface 2 brings AlphaFold-class protein structure prediction, multi-model ensemble comparison, and disease-variant interpretation to every researcher — no GPU required.

Used by researchers at 12+ institutions · No GPU required · Results in minutes
AlphaBetaGammaDelta
pLDDT
Sequence
MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFE...
Length
147 residues
Alpha completed — pLDDT 91.2
3 models running
200M+
Proteins in AlphaFold database
4
Model ensemble (Alpha, Beta, Gamma, Delta)
<2min
Average structure prediction time
7
Therapeutic areas covered
Watch a 2-minute guided tour of Surface 2
8 steps · No sign-up required · Interactive

Everything you need for structural biology research

🔬
Multi-Model Ensemble

Run Alpha, Beta, Gamma, and Delta simultaneously and compare predictions side-by-side in the built-in structure viewer.

🧬
Variant Impact Scoring

Visualise wild-type vs mutant structures with pLDDT confidence overlays and AlphaMissense pathogenicity scores.

💊
Drug Candidate Ranking

Surface AI-predicted drug-disease associations with confidence scores and DrugBank cross-references.

📊
Report Builder

Assemble publication-ready reports from structure predictions, evidence snippets, and model comparison outputs.

🦠
Disease Profile Engine

Explore gene-disease associations, mechanism hypotheses, and evidence snippets linked to live PubMed citations.

🔒
No GPU Required

All inference runs on Surface 2's managed compute layer. Researchers access results through the browser.

Built for every stage of research

USMLE · FMGE · PLAB

Understand pathophysiology at molecular level

From sickle cell polymerisation to antibiotic resistance — visualise the exact structural changes behind the mechanisms you're studying.

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Publication-grade

Build a structural biology portfolio

Run mini research projects with reproducible outputs, EvidenceLog tracking, and structured 1,500-word reports suitable for residency applications.

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Enterprise · RaaS

Full-scale pipeline automation

7 therapeutic area pipelines — oncology, rare disease, AMR, vaccine design, neurodegeneration, cardiology, pediatrics. Structured output in PDF, JSON, and DOCX.

Explore Pharma RaaS →

From sequence to insight in minutes

1
Input your target

Enter a gene name, paste a FASTA sequence, or select from 7 therapeutic area templates.

2
Select models

Choose from Alpha, Beta, Gamma, or Delta — or run all four as an ensemble.

3
Run analysis

Surface 2's compute layer runs prediction and co-folding. Live progress in the Run Monitor.

4
Explore results

Interactive 3D structure, confidence overlays, drug candidates, evidence snippets, and exportable reports.

Simple, transparent pricing

Researcher
Free
  • · Alpha model only
  • · 5 runs/month
  • · PDF export
  • · Community support
Get started free
Most Popular
ResearcherPlus
$29/mo
  • · All 4 models
  • · 50 runs/month
  • · All export formats
  • · Priority compute
  • · Report Builder
  • · Evidence log
Start ResearcherPlus
Enterprise / RaaS
Custom
  • · Unlimited runs
  • · All 7 therapeutic pipelines
  • · Dedicated compute
  • · API access
  • · SLA
  • · White-label option
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